Endocarditis is inflammation of the endocardium, the inner layer of the heart. #Osler - Osler nodes: painful red/violaceous nodules usually found on the pads of fingers and toes; #Janeway - Janeway lesions: non painful red macules found on the palms and soles; #Roth - Roth spots: a red hemorrhagic lesion of the retina with a characteristic white center representing fibrin-platelet plugs; #Splinter - Splinter hemorrhages: subungual hemorrhages appearing as linear non blanching brown-red lesions on the nail beds.
