8 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... • Cold AIHA ... • Alloimmune ... anemia • ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... (AIHA)"Cold" (usually ... #Hemolytic #Intravascular ... #hematology #anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
women • 15% of AIHA ... Viral Infection Clinical ... Diagnosis: • hemolytic ... anemiaCold ... #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Symptoms: • Asymptomatic ... associated with autoimmune ... pulmonary emboli, and ocular ... #diagnosis #rheumatology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Lymphoma - Clinical ... nodosum • Immune hemolytic ... ingestion • B symptoms ... Lymphoma Treatment ... classification #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... cytopenias (ITP, AIHA ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
: • AIHA 10% • ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... cyclophosphamide) • Hodgkin ... #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology