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diagnosis rheumatology differential management causes rash syndrome algorithm behcet classification coagulation cryofibrinogenemia dermatologic dic disease disseminated erythematosus eschar gpa granulomatosis
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Palpable purpura, Hemorrhagic ... IgM deposits • Nodular ... cutaneous vasculitis ... #Vasculitis #skin ... #dermatology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... rash (6.7%) • Hemorrhagic ... (inflamed blood ... Polyangiitis #GPA #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
aphthous ulcers, cutaneous ... , ocular, articular ... strong sign of cutaneous ... pulses, bruis, or blood ... Large Vessel: Blood
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... vasculitis) • ... Cutaneous Lesions ... Behcet syndrome (Clinical ... signs #symptoms #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
than 2 mm) of hemorrhage ... : • Complete blood ... cryoglobulins • Skin ... • Abdominal ultrasound ... Algorithm #Causes #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Strong sign of cutaneous ... pulses, bruits, or blood ... , ocular, articular ... Cogan syndrome: Ocular
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... thrombosis+Pulm HTN+skin ... , retinal, DVT, ... Paraproteinemias #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... malignancies, vasculitis ... pulmonary emboli, and ocular ... thrombi including retinal ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Erythematous, macular ... Malignancy (e.g. hematologic ... Diffuse alveolar hemorrhage
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... involvement (2%) Cutaneous ... Acral cyanosis • Hemorrhagic ... treatment #management #hematology
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