12 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... SLE) - Viral infections ... APLS • Acute Infectious ... #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... pylori test (GI symptoms ... #Diagnosis #Causes ... #Workup #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... Lyme), reactive arthritis ... SLE, psoriatic arthritis ... Joint #Pain #MSK #rheumatology ... diagnosis #arthritis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Differential Diagnosis ... to exclude are infections ... Recurrent middle ear infections ... , recent viral infection ... Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... to exclude are infections ... differential #diagnosis ... #rheumatology #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... diagnosis = vasculitis ... vs infection vs ... them, but urgent rheumatology ... #Diagnosis #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Include: • Viral infections ... (RA, Temporal arteritis ... gastric tumors • Hematology ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... Marrow Failure • Chronic ... • Parvovirus infection ... #hematology #oncology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cold insoluble globulin ... malignancies, vasculitis ... Malignancy • Infections ... #rheumatology # ... hematology