260 results
COVID-19 Life Cycle

#COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Causes of Hemolytic ... Hemoglobin - Enzyme ... Differential #Diagnosis #Causes
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Jaundice #Pathophysiology ... #Unconjugated #Causes
Causes and Pathophysiology of Hypertension

#Causes #Pathophysiology #Hypertension #Primary #Essential #Secondary #Differential

** GrepMed Recommended Text: Guyton and
Causes and Pathophysiology ... Hypertension #Causes ... #Pathophysiology
Steroid Synthesis Pathway

(OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
; pink, common enzymes ... Pathway #metabolism #pathophysiology
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Heart Failure - Causes ... , Pathophysiology ... • Other HFpEF Causes ... #HeartFailure #Causes ... #Pathophysiology
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
Synthesis Pathway Enzymes ... Synthesis #Pathway #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
coding for the enzyme ... 21-OHase causes ... the amount of enzyme ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
sulfate → Sulfatase enzyme ... Syndrome #PUBS #pathophysiology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Enzyme deficiencies ... elliptocytosis Extrinsic Causes ... Intravascular Causes ... Differential #Diagnosis #causes