30 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... the peripheral blood ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential #
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Reactive: • Anemia/blood ... #Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential ... plateletcount), peripheral blood ... #Differential # ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... (common causes ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... : - Thrombocytopenia ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... #Anemia #Differential ... Algorithm #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Platelet count ... of Peripheral blood ... WBC count and differential ... Diagnosis #Workup #Hematology