13 results
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
hypovolemic step 2 ... fludrocortisone step 3 ... = diuretic cocktail ... #diuresis #nephrology ... #algorithm
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... canagliflozin 2) ... , urearetics) 3) ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Step 2. ... administration Step 3. ... volume loss - diuretics ... Diagnosis #Workup #Algorithm ... #Nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... from tubules 3) ... Naturiesis → diuresis ... #diagnosis #nephrology ... #hyponatremia #
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acetazolamide 2) ... e.g. mannitol) 3) ... Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... renal mechanism 2) ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... #nephrology #sodium
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... #nephrology #sodium
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... increasing Na ~5mEq 2. ... 10-12 mEq/day 3. ... 3cc/kg/h, loop diuretics ... rate #management #nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm ... history Step #2 ... Uglucose Step #3 ... #Sodium #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential Algorithm ... Diuretics (discontinued ... ) 3. ... secreting tumor 3. ... Causes #Workup #Nephrology