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diagnosis rheumatology classification dermatology chronic cord fatigue myelitis nonpalpable palpable petechiae petechial physicalexam purpura rash spinal spinalcord transverse types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cause Organ Damage ... • Autoimmune diseases ... : - 10% SLE or ... syndrome) #Cryoglobulinemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HSP • Cryoglobulinemia ... Associated - SLE ... , Sjogren's ... #Diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Collagen disorders ... (lupus, RA, Sjogren's ... immunoglobulins & cryoglobulins ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... tract, and often causes ... , and SLE) • Urinalysis ... Serologies for Cryoglobulins ... #rheumatology #
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... Arthritis • SLE ... Neurologic • ... • Somatization Disorder ... Chronic Fatigue Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... : • 7%, Cryoglobulinemia ... #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... , such as SLE, atherosclerotic ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or Sjogren's ... • Infectious causes ... Vasculitis- Heroin ... Myelitis #diagnosis #management ... #neurology #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... syndrome Cord ... #diagnosis #neurology ... #algorithm
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