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diagnosis rheumatology differential inflammatory lupus manifestations myelitis neuromyelitis nmo optica sle syndromes tafro thrombocytopenia transverse vasculitides
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... (CNS) involvement ... • Sjögren syndrome ... erythematosus ... #Syndromes #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS ... (Systemic lupus ... erythematosus, ... Sjögren syndrome ... #symptoms #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... dermatomyositis, Sjogren ... and CNS • Headache ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... Symptoms (Sx) in ... purpura: strong sign ... #rheumatology #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... 6th Decades (can be ... Distal (Type I) renal ... Vasculitis: • ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... ischemia • Skin: Erythematous ... tract, and often causes ... chorioretinitis, CNS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... and/or symptoms ... Vasculitis- Heroin ... #neurology #differential
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... vasculitis - Infectious ... symptoms Histopathological ... TAFRO #diagnosis #management
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