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differential lupus sle systemic bee behcet cerebritis classification polychondritis relapsing signs symptoms syndromes tafro thrombocytopenia treatment vasculitides
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... Inflammatory causes ... • Sjögren syndrome ... vasculitides • ... #neurology #inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... dermatomyositis, Sjogren ... and CNS • Headache ... APLA/LAC: • Renal ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... Hypocomplementemia • Can cause ... #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
renal abnormalities ... Eosinophilia, asthma, chronic ... often causes arthritis ... : - Ocular inflammatory ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(25-75%): Inflammatory ... skin injury) • Neurologic ... chronic arthritis-Azathioprine ... #diagnosis #management ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
renal abnormalities ... often causes arthritis ... chorioretinitis, CNS ... : Ocular inflammatory ... #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
systemic lupus erythematosus ... (SLE), Sjögren’ ... s syndrome, ANCA-associated ... vasculitis - Infectious ... #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... Most common • Sjogren ... Heart failure • Renal ... Polychondritis #rheumatology ... #diagnosis #management
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