10 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematosus) ... erythematosus ( ... erythematosus ( ... rashErythematous
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
diagnosis and treatment ... • Systemic lupus ... erythematosus ... polychondritis • Behcet ... #differential #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus ( ... erythematosus ( ... erythematosus ( ... : Lupus (SLE), Systemic
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #erythematosus # ... signs #symptoms
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... Erythematosus ( ... : Chronic disease ... Lupusreference #druginduced ... #lupus #sle #comparison
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... syndrome (Clinical ... disease) Differential ... Arthritis, AS Treatment ... #management #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... mucositis - Rash ... : • Behçet Syndrome ... erythematosus, ... , and SLE) • Urinalysis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... Petechial or purpuric rash ... erythematosus [ ... SLE], AOSD) • Infection ... #Management #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Behcet syndrome
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... - Vasculitis- ... #neurology #differential