5 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA) is common and ... Rarely dominate the clinical ... macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
or Easy Bruising ... systemic lupus erythematosus ... Meningococcal and ... infections - Vasculitis ... pediatrics #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Systemic Lupus Erythematosus ... cutaneous lupus erythematosus ... (ACLE) • Erythematous ... cutaneous lupus erythematosus ... • Erythematous
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
, such as IL-1 and ... Systemic lupus erythematosus ... rash) • Heart, ... lung, and kidney ... systemic lupus erythematosus
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Progressive symptoms