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diagnosis disease erythematosus hematology lupus systemic agglutinin autoantibodies behcet chronic cll lymphocytic management mimickers syndrome workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... anemia 4% - Myositis ... Auto-Antibodies ... autoantibodies #signs ... rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rash • Erythematous ... alopecia Differential ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... leukemia • Lung
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Behcet disease) Differential ... tears, Ischemia, Leukemia ... diagnosis #management #signs ... #symptoms #rheumatology
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