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diagnosis symptoms erythematosus lupus activation ana antibodies antinuclear behcet cryoglobulinemia gca giantcell hematology macrophage mas patterns sjogrens temporal types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... lupus erythematosus ... diagnosis #types #classification ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... #systemic #erythematosus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... Classification: ... rash • Erythematous ... permanent alopecia Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology # ... classification
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... (SLE), Systemic ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... as SLE, atherosclerotic ... purpura: Strong sign ... , mucositis • Rash ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Petechial or purpuric rash ... [SLE], AOSD) • ... #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... Diagnosis = clinical ... very remarkable w/differential ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Arthralgia and Arthritis ... #Rheumatology # ... Diagnosis #Management
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