11 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... lupus erythematosus ... #classification ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... , Vasculitis, Purpura ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... rashErythematous ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis: Systemic ... Symptoms (Sx) in ... differential #diagnosis ... #rheumatology # ... classification
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... clinically significant ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #diagnosis #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... as SLE, atherosclerotic ... purpura: Strong sign ... #Differential #Diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... fasciculations Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... Diagnosis = clinical ... diagnosis = vasculitis ... #Symptoms #Diagnosis ... #Management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... vasculitis - Infectious ... symptoms Histopathological ... #management #rheumatology