29 results
Gynecomastia - Differential Diagnosis a
nd Workup Algorithm
Gynecomastia is common in clinical practice, affecting ~50% of males
LFTs, Prolactin, Testosterone ... , HCG, Estradiol
Anastrozole is a Selective non-steroidal aromatase Inhibitor. Used for the treatment of breast cancer in postmenopausal
androstenedione and testosterone ... to estrone and estradiol ... significantly lowers serum estradiol
#LH
#Cholesterol
t
cholesterol desmolase (#thecal cells)
V
3ß-hydroxysteroid
dehydrogenase
Pregnenolone
Progesterone
17a-hydroxylase
17-Hydroxypregnenolone
17,20-lyase
Dehydroepiandrosterone
3ß-hydroxysteroid dehydrogenase
#Androstenedione
17B-hydroxysteroid dehydrogenase
FSH
V
#Testosterone
Đ
#aromatase
(granulosa cells)
V
#Estradiol
dehydrogenase FSH V #Testosterone ... granulosa cells) V #Estradiol
Gender Affirming Care
Modalities of Gender Affirmation
 • Legal - Can include updating: Birth certificate, Social Security
GnRH antagonists, Estradiol ... , Testosterone,
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
FSH/LH -> Decr estradiol ... females, Decr testosterone
ACTH
LH
Cholesterol
cholesterol desmolase
Pregnenolone
17a-hydroxylase 17 Hydroxyregnenolone
17,20-lyase
3B-hydroxysteroid
dehydrogenase
3B-hydroxysteroid
dehydrogenase
17a-hydroxylase
#Progesterone
17-Hydroxyprogesterone
17,20-lyase
21ß-hydroxylase
21ß-hydroxylase
11-Deoxycorticosterone
11-Deoxycortisol
11ß-hydroxylase
11ß-hydroxylase
#Cortisol
#Dehydroepiandrosterone
#DHEA
3ß-hydroxysteroid
dehydrogenase
个
#Androstenedione
#17B-hydroxysteroid
#dehydrogenase
#Testosterone
#aromatase
#FSH
#Estradiol
#5a reductase
#Corticosterone
aldosterone synthase
#Aldosterone
Angiotensin ||
#Dihydrotestosterone
(DHT)
dehydrogenase #Testosterone ... aromatase #FSH #Estradiol
Differential Diagnosis and Workup for Male Gynecomastia:
Medications: spironolactone, ketoconazole, finasteride, alcohol, opiates, INH, steroids (testosterone, estrogen),
INH, steroids (testosterone ... secrete beta-hcg or estradiol
Exogenous Testosterone Side Effects
 • Mood disorder, Depression, Aggression
 • ↑ Erythropoiesis
 • Hypogonadism +/-BPH, prostate
Exogenous Testosterone ... #Exogenous #Testosterone
This is a quick overview of hormonal acne treatment for the medical student and resident.

Keep in
include: Ethinyl Estradiol ... Norgestimate Ethinyl Estradiol ... Iron) Ethinyl Estradiol ... Drospirenone Ethinyl Estradiol ... acetate/ethinyl estradiol
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
-> Increased Testosterone ... -> Testosterone ... Conversion of testosterone ... pituitary -> Decr Testosterone