18 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... Clinical Manifestations ... Diagnosis #Management #Hematology ... Manifestations #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... (CVID, WAS), (neurologic ... - Bone marrow evaluation ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... for secondary causes ... Differential #diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... management of SLE • Evolution ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... cutaneous-DIL • Evolution ... management of SLE • Evolution
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... Approach (when evaluation ... 109 mm Hg) with clinical ... Neurologic disorders ... #Hypertension #Workup
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
BCNIE relies on evaluation ... antimicrobials, clinical ... but important causes ... factors: - Serology ... #differential #workup
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Leukemia • Corticosteroid ... likelihood of negative clinical ... count on initial evaluation ... neutrophil #WBC #CBC #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... inhibitors under evaluation ... treatment #summary #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... presentation, temporal evolution ... status, and focal neurologic ... Demyelinating disease caused ... InfectiousDiseases #Neurology