433 results
diagnosis management differential algorithm clinical pharmacology pathophysiology treatment causes cardiology nephrology table hematology endocrinology signs symptoms gastroenterology msk rheumatology antibiotics
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Pathophysiology EXOGENOUS ... components Exogenous ... , IFN, IL-6 ENDOGENOUS ... vasculature via: • Active ... organs CNS - Endogenous
Staging of Skin Mottling Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... endogenous vasoconstriction ... not additional exogenous
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: → Exogenous ... pro-inflammatroy mediators (Endogenous ... Pyrogen) → Endogenous ... vasculature via: • Active ... circumventricular organs CNS: Endogenous
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm Exogenous (ACTH-independent) Endogenous • ACTH-dependent: - ACTH-secreting
Diagnosis Algorithm Exogenous ... ACTH-independent) Endogenous
Hypoglycemia - Evaluation Algorithm Interpreting Hypoglycemia Labs - the patient must be hypoglycemic at the time of
Proinsulin - Is it endogenous ... → Exogenous Insulin
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Phosphate Load: • Exogenous ... Fosphenytoin • Endogenous
Opioid Use Disorder Medications - Pharmacokinetics Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
low intrinsic activity ... the effects of exogenous
Exogenous Testosterone Side Effects • Mood disorder, Depression, Aggression • ↑ Erythropoiesis • Hypogonadism +/-BPH, prostate
Exogenous Testosterone ... BrighamChiefs #Exogenous
Cephalosporins Cephalosporins are bactericidal beta-lactam antibiotics derived from the fungus Acremonlum— they disrupt peptidoglycan formation in
They have no activity ... predominantly active ... progressively more active ... gram-positive activity
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