55 results
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... production • Actively ... maintained fever CAUSES ... #Differential #Causes ... Checklist #Diagnosis #Management
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia
Expected or unexpected major haemorrhage

❶ Call for
with them): • Activate ... required. ❻ Begin active ... equipment. ❽ Discuss management ... an appropriate clinical ... Anesthesiology #Anesthesia
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... of underlying disease ... why LR does not cause
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... normal in mild cases ... #treatment #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis: • Endogenous ... characteristic features Clinical ... TB #Diagnosis #Management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... signs/symptoms of active ... decreased reflexes Pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
Characterizing activity ... pathway in the clinic ... understanding of pathophysiology ... classifications for diseases ... signature #diagnosis #management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... intensive ❾ Begin active ... Plan admission to critical ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis: • Endogenous ... characteristic features Clinical ... TB #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management