11 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... node and AV node activity ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... node and AV node activity ... #Pharmacology # ... #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
For my UME micro course, I made a figure that captures this terminology and lets learners
the spectrum of clinically ... important drug classes ... does not equal clinical ... #antibiogram #pharmacology ... management #spectrum #table
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... Pathophysiology: ... angular gyrus Clinical ... #neurology #diagnosis ... #pathophysiology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Clinically Significant ... wort - Increases activity ... vera, Licorice - Causes ... arrhythmias Class I Antiarrhythmic ... #DDI #table #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... symptoms are not caused ... Self-limiting, chronic but stable
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... - Causes progressive ... by decreasing activity ... Lateral #Sclerosis #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Clinical Manifestations ... continuous motor unit activity ... Continuous motor-unit activity
Medications Used in the Abortive Treatment of Ongoing Seizure Activity in the Emergency Department

INITIAL THERAPY
 -
Ongoing Seizure Activity ... Phenytoin - May cause ... #Medications #Neurology ... #Pharmacology # ... Dosing #Table