40 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... ß-glucocerebrosidase activity ... in GBA1 gene Clinical ... #Diagnosis #Signs ... #Symptoms
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Clinical History ... hypertension) - Symptoms ... Inflammatory diseases ... #Differential # ... Causes
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... /symptoms of active ... decreased reflexes Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Pathogenesis and Clinical ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic acid is an endogenous ... with exercise/activity ... of underlying disease ... why LR does not cause ... Acidosis #types #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... bile ducts Differential
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... : • Active adolescents ... exacerbated with activity ... tibial tuberosity Differential ... tear (similar symptoms
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - Differential ... hemorrhage, and seizure activity ... • Signs/Symptoms ... • Signs/Symptoms ... #differential #
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... • Other rare causes ... Cardiovascular disease ... Overproduction #diagnosis #signs ... #symptoms #endocrinology