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management treatment hematology rheumatology signs symptoms vasculitis acromegaly classification coagulation cryoglobulinemia cryoglobulins dic differential disseminated endocrinology eschar henochscholeinpurpura hsp iga
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can activate ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Henoch-Schönlein purpura) • Cutaneous
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... increased B-cell activity ... renal failure Clinical ... symptoms are not caused
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Pathophysiology ... Clinical Manifestations ... continuous motor unit activity ... Continuous motor-unit activity
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... involvement (2%) Cutaneous ... #Coagulation #diagnosis ... #causes #treatment
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Pathogenesis and Clinical ... response) - Cutaneous ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... malignancy) • Cutaneous ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... or refractory cases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... noncompliance • Clinical ... initiation Clinical ... • Persistently active ... #Inflammatory #Syndrome
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... mucor cases may ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
disease that is caused ... • Sexual activity ... three weeks Clinical ... Monkeypox #MPOX #Diagnosis ... #Management #Dermatology
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