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diagnosis ammonia differentiation hematology hyperammonemia management oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... febrile neutrophilic dermatosis ... initiation • Differential
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... - Significant endogenous ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
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