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hematology management blood classification differential reactions extravascular hemolysis hodgkins intravascular leukemia lymphoma thromboticthrombocytopenicpurpura transfusion ttp workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... anemia): ... Extravascular #Causes ... #hematology #anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... maculopapular rash ... Causes purpura & ... diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... #Transfusion #diagnosis ... #management #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... prosthetic valve • Transfusion ... #Diagnosis #causes ... classification #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
is the diagnostic ... Fibrin degradation products ... result in severe anemia ... anemia Indirect ... #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... anemia • Pain ... genes and gene products ... • PET scan - activity ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Tyrosine Kinase activity ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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