9 results
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
acid is an endogenous ... with exercise/activity ... why LR does not cause ... as an arterial lactate ... pathophysiology #classification
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
- Classification ... Anaerobic muscular activity ... delivery: Hypoxemia, Anemia ... #Acidosis #Classification ... #TypeA #TypeB #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... Elevation, Lactic ... Causes of Lactate ... 30mmHg) - Severe anemia ... #typea #typeb #classification
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... immune hemolytic anemia ... elevation Serum lactate ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... - Drugs (Beta lactam ... Extravascular #Causes ... #anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... propylthiouracil) - β-lactam ... #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... ) Classification ... Hodgkin Lymphoma Workup ... • PET scan - activity
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... gram-negative bacillus cause ... initially with a beta-lactam-beta-lactamase ... Canimorsus #Skin #Rash #dermatology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
CT must show no lytic ... • No CRAB - no anemia ... lesions • Lactate ... Oncology #Diagnosis #Workup ... #Hematology