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diagnosis hematology algorithm differential management classification folicacid glomerular macrocytic nephrology nephrotic nutrition aafp ascorbicacid common cvid deficiency disease glomerulonephritis hodgkins
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
in Hemolytic Anemia ... Extravascular Hemolysis ... Carboxyhemoglobin #Hemolytic ... #Testing #workup ... #hemolysis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... haptogbbulin #Hemolysis ... #Hemolytic #Anemia ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... out an immune hemolytic ... the severity of hemolysis ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Deficiency • Folate ... Diagnosis #Algorithm #Causes ... #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Hemorrhage or hemolysis ... the most likely cause ... recovery also causes ... of the initial work-up ... #VitaminB12 #Folate
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... , exogenous erythropoietin ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate ... pregnant have hemolytic ... anemia, or psoriasis ... that can cause ... differential #diagnosis #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
, anemia, edema, ... Loss of teeth Anemia ... lead to iron and folate ... contribute to nonimmune hemolysis ... , or any other cause
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... disorders that activate ... infections are common causes ... #workup #diagnosis
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