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diagnosis hematology management algorithm differential macrocytosis oncology aafp anesthesia anesthesiology checklist classification common cvid elevatedmcv folicacid hodgkins homocysteine hyperthermia hypogammaglobulinemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
acute blood loss, hemolysis ... , exogenous erythropoietin ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic ... #Macrocytic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Drugs Oval Macrocytes ... Myelodysplastic Syndromes ... Rule out B12 and Folate ... #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... Hemorrhage or hemolysis ... the most likely cause ... recovery also causes ... #Folate #FolicAcid
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
MCV - >96fL - "Macrocytic ... B12 deficiency, Folate ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for this enzyme activity ... result in severe anemia ... anemia Indirect ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Workup: • Complete ... Treatment: Goals: Treating ... #diagnosis #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
• Excessive heating ... production • Actively ... maintained fever CAUSES ... hyperthermia crisis (late ... Diagnosis #Management #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... disorders • Testing ... diazepam • EMG testing ... antibody that works
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... • PET scan - activity
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