22 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
: • Pauci-Immune ... Cryoglobulinemia) • Immune ... allopurinol), Infection ... Investigations • Labs: CBC ... DAH, rule out infection
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... required until immune ... status, and focal neurologic ... differential #diagnosis #AIDS
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Inflammatory Syndrome ... (IRIS) - Pathophysiology ... factors: - Low CD4 ... #Inflammatory #Syndrome ... #AIDS
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... accumulation of clinical ... Assessment • Clinical
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... • Enteroviral infections ... • Herpes virus infections ... MRI lesions and clinical ... #neurology #noninflammatory
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... preceding infection ... management #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... noncompliance • Clinical ... initiation Clinical
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... diagnosis #management #neurology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... Findings - Infectious ... cell-mediated immune ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Preeclampsia, Eclampsia, Infection ... Etiology: • Pathophysiology ... Diagnosis: • Infection ... Seizures: Treat with AEDs