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diagnosis differential management als amyotrophic associated barre bee crypto cryptococcal dementia disorder guillain guillainbarre infections infectiousdiseases inflammatory lateral manifestations meningitis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... • IRIS might ... should be based on clinical ... required until immune ... patients with IRIS
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... syndrome of HAD ... and with low CD4 ... disorder #dementia #AIDS ... #Neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... initiation Clinical ... pleural effusions, CNS
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... nervous system: Brain ... Lack of UMN/LMN signs ... Polymyositis • Immune ... parainfluenza, Coxsackie, HIV
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... affecting the Brain ... nervous system (CNS ... pachymeningitis • HIV ... clinical consistent
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
collapse Immune ... Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... contrast enhancement Brain ... or abruptly • CN
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... : • Immune response ... Campylobacter jejuni - HIV ... Paresthesias: Hands
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... cells are the immune ... MRI: Brain, cervical ... motor neurons - IV ... Lateral #Sclerosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Transverse Myelitis - Clinical ... • Bilateral signs ... simplex virus, HIV
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
low glucose) CNS ... organism (soap bubble sign ... likely due to IRIS ... meningitis #T2 #MRI #Brain ... #clinical #radiology
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