97 results
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Exogenous antigen ... associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... harmful -> Th Cells activate ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
Mottling suggests active ... not additional exogenous ... Mottling #Staging #Clinical ... #Diagnosis #Stages ... #Clinical
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... → Exogenous Pyrogen ... vasculature via: • Active ... Rigors #Bacteremia #Pathophysiology ... InfectiousDiseases #Diagnosis
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... cytotoxic cell activity ... #Inflammation #pathophysiology ... #immunology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... antigens and thereby activate ... naive CD4 T cells ... #asthma #pathophysiology ... #inflammatory #immunology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... loop diuretics actively ... #Differential #Diagnosis
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Lactic acid is an endogenous ... with exercise/activity ... #differential #diagnosis ... #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... present Ag to CD4 ... helper T cells and activate ... Humoral #Immunity #pathophysiology ... #immunology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
- Differential Diagnosis ... DM (visit 2), Diagnosis ... based on repeat clinic ... • Nephritic syndrome ... Steroids (Cushing's, exogenous