23 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... -> Particular CD4 ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
and Management Summary ... Pathophysiology ... epidermis from dermis Clinical ... not feasible CMC ... #Management #dermatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management Summary ... extrapulmonary cases Clinical ... decreased reflexes Pathophysiology ... intervention CMC ... #Management #Summary
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- Summary Acute ... Guillain-Barre Pathophysiology ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #diagnosis #management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... and Management Summary ... Clinical features ... Budd Chiari syndrome ... Hb levels and CBC
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... management #treatment #summary
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... Clinical Presentation ... Atorvastatin Diagnosis ... IU/I • SAMS clinical ... toxicity #myopathy #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... and Management Summary ... Pathophysiology ... Clinical Manifestations ... - Diagnosis: