20 results
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Exogenous antigen ... associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology ... #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism ... dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology ... immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Pathogenesis and Clinical ... cell activity #Inflammatory ... #Inflammation #pathophysiology ... #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... -> Particular CD4 ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... release the pro-inflammatory ... secretion • Inflammatory ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Guillain-Barré syndrome ... antisynthetase syndrome ... Statins → Inflammatory ... IU/I • SAMS clinical
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... Prodrome: pruritic, inflammatory ... not feasible CMC
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Syndrome (IRIS) ... - Pathophysiology ... factors: - Low CD4 ... #Syndrome #IRIS ... #Pathophysiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Gastrointestinal inflammatory ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology
Haglund Syndrome - MSK Radiology
Imaging Findings:
 • The Haglund Deformity (enlarged superior margin calcaneal posterior process)
Haglund Syndrome ... 11 mm TV, 7mm CC ... diagnosis: • Inflammatory ... #Heel #clinical ... #mri #clinical