14 results
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Exogenous antigen ... associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... -> Particular CD4 ... Stevens-Johnson Syndrome ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... present Ag to CD4 ... Humoral #Immunity #pathophysiology ... #immunology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... treatment #summary #rheumatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative clinical ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Virologic and immunologic ... noncompliance • Clinical ... initiation Clinical ... #Inflammatory #Syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... Clinical Features ... titers > 1:80 • CBC ... Erythematosus #Diagnosis #Rheumatology