11 results
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... unclear (often the case ... AI Measure ACTH ... #Adrenal #Insufficiency ... #Test #Endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... - Secondary adrenal ... #Algorithm #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... Hyperkalemia is ... Causes of Secondary ... #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... (Secondary): • ... #AI #Differential ... #Causes #endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
- Differential Diagnosis ... Workup Algorithm ... or tuberculosis Secondary ... apoplexy • Isolated ACTH-deficiency ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - ... Differentiate primary vs secondary ... consistent with secondary ... ) #Adrenal #Insufficiency ... #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
aldosterone - Low in cases ... antibody test Secondary ... Evaluation #laboratory #diagnosis ... #testing #endocrinology ... #workup
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Serum DHEAS Diagnosis ... /dL -> Primary AI ... ug/dL Primary AI ... addisons #disease #endocrinology ... #diagnosis #signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... and Differential Diagnosis ... Vasculitis • Endocrinologic ... Hyperthyroidism, Hypercalcemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , RTA Type IV, AI ... reabsorption) Workup ... levels, Cortisol+ACTH ... only if no clear cause