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differential hematology management neurology pulmonary syndrome workup afferent algorithm antimda5 antimda5dm arteritis arthritis autoimmune behcet bronchiectasis chronic classification clinical cll
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Relative Afferent Pupillary Defect This maneuver of intermittent light stimulus is called the alternating light test or
It is a clear sign ... very sensitive diagnostic ... regarding the cause ... afferent pathway injury ... Pupils #MacrusGunn #PhysicalExam
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 Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
- Differential Diagnosis ... Traumatic brain injury ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... -74%] • Blood tests ... #dermatology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to local skin injury ... meningitis), MCC CNS symptoms ... is a skin prick test ... #management #signs ... #symptoms #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchial wall injury ... inflammation Symptoms ... Nasal polyps and signs ... parenchyma Diagnosis ... #differential #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... the “Chewing gum test ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... ) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... workup #oncology #hematology
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