When to look for clonal/neoplastic hypereosinophilia (HEo)?
- Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer, ...)
- Clinical symptoms (Male gender, Splenomegaly)
- Hemogram abnormalities (Cytopenia, Other cell proliferation, monocytosis)
- Myelogram/BM biopsy (Mast cells (FIP1L1), Myelofibrosis, Blastosis)
- Incr Cobalamin, Incr Tryptase
- Resistance to glucocorticoids
By Dr. Julien Rohmer via Dr. Benjamin Terrier @TerrierBen
#Neoplastic #hypereosinophilia #HEON #Diagnosis #Signs #Hematology #Workup
Dr. Gerald Diaz
@GeraldMD
· 5 years ago
