11 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... HBV infection, HIV ... Labs/Diagnosis: ... #types #classification ... #rheumatology #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... - HCV - HIV ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura (HSP ... on tuberculosis treatment ... pain involving knees ... clinical #photo #dermatology ... #skin #rash #physicalexam
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Diagnosis: • Dry ... amyloidosis, PAH Skin ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Growers (Runyon Classification ... Hematologic malignancy ... Imaging, high res
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... Differential Diagnosis ... cord infarct • HIV ... stimulation of skin ... axial T1 and T2 Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... Hepatomegaly • Skin ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • Cogan Syndrome ... Cryoglobulins • HIV ... #rheumatology # ... classification
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
: 2 weeks to a few ... weight loss • Skin ... Albuminuria, nephrotic syndrome ... individuals with HIV ... Syphilis #stages #diagnosis