16 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Henoch-Schönlein purpura) - Treatment ... algorithm for the ... Treatment remains ... #Treatment #Rheumatology ... #Vasculitis #Algorithm
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... Factors: • SICU ... > MICU, ♀, ↑Age ... complex → plt activation ... #Treatment #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
hemoptysis • Dyspnea ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... can mimic common infections ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
hemoptysis • Dyspnea ... Tuberculosis Treatment ... Initiating Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... with chronic HBV infections ... #Diagnosis #Management ... #Treatment #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Differential Diagnosis: Infection ... organ dysfuxtion, ICU ... APML #diagnosis #management ... #hematology #oncology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... Presents as dyspnea ... Infection - Infection ... Transfusion #diagnosis #management ... #hematology #reactions