88 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... Prolonged PT and aPTT ... #Abnormal #PT #aPTT
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... , FVII, FIX, FX ... , FVII, FIX, FX) ... #Abnormal #PT #aPTT
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... = Intrinsic = APTT ... #Coagulation #Cascade
Coagulation Cascade - Anticoagulant Targets
Here's the brief overview of where the main anticoagulants work on the
Coagulation Cascade ... anticoagulants work on the cascade ... Warfarin - II, VII ... #Coagulation #Cascade
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... Prolonging the PT or APTT ... cause of Prolonged APTT ... ISNeducation #Abnormal #APTT
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... complexes with FVIIa ... TF-FVIIa also activates ... #Coagulation #Cascade ... thrombin #clot #PT #PTT
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... vWF #thrombin #ptt
Simplified Coagulation Cascade and Differential Diagnosis

#Coagulation #Cascade #Differential #Diagnosis #Intrinsic #Extrinsic #Pathway #Hematology
Simplified Coagulation Cascade ... #Coagulation #Cascade
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... Diagnosis Algorithm aPTT ... #Elevated #aPTT
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged aPTT ... PT - Prolonged aPTT ... Coagulation #Abnormal #APTT