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hematology causes pt abnormal anticoagulant anticoagulation aptt cascade clot dabigatran dic differential disseminated edoxaban heparin inhibitor intravascular management models pathophysiology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... Congenital intrinsic coagulation ... intravascular coagulation ... Prolonged #Causes #diagnosis ... differential #hematology #coagulation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... complexes with FVIIa ... TF-FVIIa also activates ... clot #PT #PTT #diagnosis ... thrombin #inhibitor #Apixaban
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... levels of factors VII ... is simultaneous coagulation ... Thromboembolism (7%) • CNS ... #diagnosis #causes
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