83 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Deficiency of Factor ... Deficiency of Factor ... Medications - Heparin ... • Acute DIC - Septic ... Summary #table #comparison
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... Thrombocytopenia - Normal ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... - APTT < 1.5 x normal
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... VIII level NORMAL ... Acquired: • Heparin ... PT/NORMAL PTT:
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
could be multiple factors ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... Decreased factor ... amyloidosis #Abnormal
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin ... Jcortesizaguirr #Abnormal
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Arterial Phase, Portal ... Dysplastic nodule, Hepatic ... Liver #Lesions #Hepatic ... Contrast #CT #MRI #POCUS ... differential #diagnosis #comparison
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... Warfarin - Selective factor ... Direct thrombin (factor ... medications #doac #comparison
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Differential Diagnosis Algorithm ... Portal Hypertension ... Hypertension - Hepatic ... Hypertension - Post-Hepatic ... Differential #Diagnosis #Algorithm
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
Hypoaldosteronism (Normal ... Inhibitors - Chronic heparin ... Aldosterone Resistance (Normal ... or High Renin, Normal ... #Aldosterone #Comparison
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
Portal venous gas ... on hepatic ultrasound ... of air in the hepatic ... ischemia, perforated peptic ... hepatology #liver #pocus
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