49 results
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics
1,3 ß-D-glucan:
 • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... and pneumocystis False ... inconsistently in other fungi ... • False positives ... #Fungi #Fungal
The test characteristics of the heterophile antibody (AKA the monospot test) are not perfect and can
can lead to both false ... positive and false ... instead using EBV ... Mononucleosis #EBV
The test characteristics of the heterophile antibody (AKA the monospot test) are not perfect and can
can lead to both false ... positive and false ... instead using EBV ... Mononucleosis #EBV
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... component of many fungi ... breakthrough IFI in HM • False ... recipients, CGD pts • False ... Sara Dong #Fungal
Outcomes in Severe Hyponatremia Treated With and Without Desmopressin.

Am J Med. 2018 Mar;131(3):317.e1-317.e10. doi: 10.1016/j.amjmed.2017.09.048. Epub
Am J Med. 2018 Mar ... aakashshingada #EBM
PIVOTAL Visual Abstract - Intravenous Iron in Patients Undergoing Maintenance Hemodialysis - January 31, 2019

N Engl
2019 N Engl J ... VisualAbstract #EBM
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Specificity and False ... component of many fungi ... BAL samples • False ... closely related fungi ... Galactomannan #Fungal
SALT-ED Trial - Balanced Crystalloids versus Saline in Noncritically Ill Adults

N Engl J Med 2018; 378:819-828
Adults N Engl J ... VisualAbstract #EBM
(1,3)-β-d-glucan
Abundant cell wall polysaccharide, found in most fungi, except cryptococci, zygomycetes (mucor, rhizophus) and blastomyces.
Sensitivity 64%-93%;
found in most fungi ... Specificity 87%-100% False ... blood • Certain fungus ... 3)-ß-d-glucan False ... glucan #betad #fungal
Mortality after Fluid Bolus in African Children with Severe Infection - June 30, 2011 N Engl
30, 2011 N Engl J ... NEJMoa1101549 #EBM