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diagnosis differential management cardiology fungal syndrome workup disease endocrinology infectiousdiseases laboratory neurology treatment adrenal betadglucan causes covid19 criticalcare ebm galactomannan
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... cut-offs defined in clinical ... >90% (In most clinical ... Galactomannan #Fungal #Testing ... #FalsePositives
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
dermatidis • Sensitivity ... cut-offs defined in clinical ... : Mucorales • Sensitivity ... disease - Sensitivity ... Frozen ice-pops (in setting
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... HIV/AIDS, CGD) Clinical ... Diagnosis and Testing ... Galactomannan sensitivity ... associated with low sensitivity
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
-> Serological Testing ... Fungal (Histoplasma/Aspergillus ... -> Serological Testing ... -> Serological Testing ... Diagnosis #Management #Algorithm
Ohle R et al. Clinical Examination for Acute Aortic Dissection: A Systematic Review and Meta-analysis. AEM
Clinical Examination ... Dissection #Aorta #Testing ... Signs #Accuracy #Sensitivity
Abdominojugular (Hepatojugular) Reflux Described by Pasteur in 1885 as a physical sign of TR. Still useful for
with reasonable sensitivity ... Resource limited setting ... #PhysicalExam #Clinical
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 Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... value of 0.0115, sensitivity ... Thus, further testing ... #Differential #Algorithm
Traditionally, we have been taught to examine for Kernig’s and Brudzinski’s signs when examining patients with
JAMA rational clinical ... evidence and low sensitivity ... they do recommend testing
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... for AI (but low sensitivity ... require Cosyntropin testing ... Insufficiency #Algorithm
Carpal Tunnel Syndrome: Pathogenesis and clinical findings • Dysthesias - Tingling, burning, or painful sensation at
Pathogenesis and clinical ... Thenar muscle wasting ... Hypalgesia - Diminished sensitivity
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