13 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... #management #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... likely to cause ... glucocorticoids - can cause ... #Gravis #diagnosis ... #management #neurology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... Myasthenia gravis ... such as cogan sign ... tumor, and always ask ... ophthalmology #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Demyelinating Disease (MS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #diagnosis #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... Sjögren syndrome, Myasthenia ... gravis, Many others ... Manifestations #diagnosis #neurology ... #symptoms #signs
Froment’s Test for Ulnar Nerve Palsy

This tests for pinch grip weakness caused by ulnar nerve palsy,
for pinch grip weakness ... caused by ulnar ... Froment's Sign is ... Jeanne’s sign is ... #Froments #Sign
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Postsynaptic: Myasthenia ... Gravis - Lack ... of UMN/LMN signs ... aminotransferases • Serology ... Differential #Diagnosis #neurology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
- Symptoms and Signs ... Muscles • Weakness ... Amy Chung, MD, MSc ... Hyperthyroid #Symptoms #Signs ... #Diagnosis #endocrinology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... hyperthyroidism #causes ... #differential #endocrinology ... #signs #symptoms