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diagnosis hematology management differential leukemia chronic cll hiv hodgkins lymphocytic neurology pathophysiology signs syndrome acute aids algorithm alkpos als amyotrophic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... of about three cases ... ingestion • B symptoms ... (90-95% of cases ... classification #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... type (B cell, T cells ... Nodal disease: B symptoms ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Non-Hodgkin's Lymphoma ... Reed-Sternberg Cells ... • Hodgkin's Lymphoma ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... and secondary lymphoid ... Small lymphocytic lymphoma ... of large cell lymphoma ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... diagnosis #workup #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... Epidemiology: Lymphoma ... regimen Signs/Symptoms ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
Anaplastic large cell lymphoma ... advanced stage + B symptoms ... ) • Donut cells ... than one • Rare cases ... Anaplastic #largecell #lymphoma
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... Splenomegaly 5) Symptoms ... to large cell lymphoma ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
and primary CNS lymphoma ... less than 200 cells ... Demyelinating disease caused ... Primary CNS Lymphoma ... for primary CNS lymphoma
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... Muscle twitching (fasciculations ... BULBAR: Tongue fasciculations ... Common Symptoms ... Escorial criteria uses
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