277 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
, muscle atrophy ... twitching (fasciculations ... BULBAR: Tongue fasciculations ... conditions listed in differential ... #management
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Sensory Changes - Differential ... Diagnosis Algorithm ... Neuropathy - Atrophy, Fasciculations ... Myopathy - Proximal muscle ... #Diagnosis #Algorithm
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Sensory Changes - Differential ... Diagnosis Algorithm ... Neuropathy - Atrophy, Fasciculations ... Myopathy - Proximal muscle ... #Diagnosis #Algorithm
Upper Versus Lower Motor Neuron Findings

Denervation near the target muscle fibers (lower motor neuron disease) results
near the target muscle ... stimulation leads to muscle ... activity produces fasciculation ... Versus #Findings #Diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
posturing • Fasciculations ... can happen) • Muscle ... reflexes (at those muscles ... Radiculopathy #MSK #diagnosis
Jaw Clonus on Physical Exam

A 24-year-old man presented with progressive dysphagia, dysarthria, and weakness in his
jaw clonus and muscle ... fasciculations, ... consistent with a diagnosis
Algorithm for the Evaluation of Dysphagia:Oropharyngeal:
- Characterized by difficulty initiating swallowing and accompanied by choking/coughing, nasopharyngeal
anatomy: Tongue, muscles ... cricopharyngeus muscle ... coordinated by medulla #Diagnosis ... #Differential # ... Extraluminal #Algorithm #Differential
Critical and Emergent Causes of Neuromuscular Weakness
CRITICAL DIAGNOSES 
 - Cerebral cortex or subcortical 
 -
Weakness CRITICAL DIAGNOSES ... junction - Muscle ... EMERGENT DIAGNOSES ... Peripheral nerve - Muscle ... Neuromuscular #Weakness #Differential
Causes of Rhabdomyolysis - Differential Diagnosis
 • Drugs & Toxins (Statins, alcohol, cocaine)
 • Direct Muscle
Rhabdomyolysis - Differential ... Diagnosis • Drugs ... exercise) • Muscle ... Rhabdomyolysis #Differential ... #Diagnosis #Causes
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
Myopathies #ESR #CK #Differential ... diagnosis of myopathy ... Dermatomyositis #muscle ... Hypothyroid myopathy #Muscle ... Cocaine-induced myopathy #Muscle