2395 results
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Algorithm Labs: Ferritin ... Gastrectomy, WHDA syndrome ... Diagnosis #Algorithm #ferritin ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... dehydrogenase • ↑ Ferritin ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... cell activity • Ferritin ... management #treatment #hematology
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Saturation, ↓ Ferritin ... Saturation, ↑-nl Ferritin ... Saturation, ↓-↑-nl Ferritin ... Saturation, ↑-nl Ferritin ... #differential #hematology
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
histoplasmosis #Ferritin ... Differential #Diagnosis #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... suspect underlying hematologic ... Hypereosinophilic #Syndrome ... #HES #Hematology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Differential Diagnosis Ferritin ... > 1000 Ferritin ... hepcidin prevents ferritin ... Common Causes Ferritin ... Hematologic Malignancy
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... anemia #diagnosis #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Globin Synthesis Ferritin ... Dietary Deficiency) Ferritin ... Inflammation Ferritin ... Algorithm #Causes #Hematology
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
synthesis • Ferritin ... #Anemia #IDA #ferritin ... Fe #diagnosis #hematology