87 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH ... lab findings in HLH ... : ↑↑ ferritin, Anemia ... consistent with HLH ... cell lines) • ↑ ferritin
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
HLH 2. ... histoplasmosis #Ferritin
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Differential Diagnosis Ferritin ... > 1000 Ferritin ... hepcidin prevents ferritin ... HLH or Adult Onset ... In adults, HLH is
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... / Diagnosis: HLH ... cell activity • Ferritin ... • Bicytopenia Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... dysfunction, ↑ Ferritin ... • Familial HLH ... Unknown cause Treatment ... diagnosis #management #treatment
IDSA Recommended antimicrobial regimens for treatment of patients with Lyme disease.

#Management #InfectiousDiseases #Antibiotics #LymeDisease #Treatment #Regimens
IDSA Recommended ... antimicrobial regimens for treatment ... #LymeDisease #Treatment ... #Regimens #IDSA
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Lymphohistiocytosis #Management #Treatment
Summary of Recommendations for the Treatment of Aspergillosis - IDSA Guidelines
 - Invasive syndromes of Aspergillus
Recommendations for the Treatment ... Aspergillosis - IDSA ... Aspergillosis #Treatment ... #medications #IDSA
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
IDSA Aspergillosis ... Treatment • Invasive ... Aspergillosis #Treatment ... #pharmacology #IDSA
IDSA Algorithm for Management of Acute Uncomplicated Cystitis
Approach to choosing an optimal antimicrobial agent for empirical
IDSA Algorithm for ... for empirical treatment ... Uncomplicated #Cystitis #IDSA ... Algorithm #Management #Treatment