3083 results
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm
Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Diagnosis and Treatment ... Algorithm Diagnosis: Ferritin ... absolute ID) OR Ferritin ... heartfailure #diagnosis #management ... algorithm #cardiology #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
CRP, AST+ALT, ferritin ... AOSD: F>M, low ferritin ... synovitis (40%) Treatment ... rheumatology #diagnosis #management ... #treatment
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Diagnosis: Ferritin ... absolute ID) OR Ferritin ... functional ID) Treatment ... heartfailure #diagnosis #management
Treatment of Restless Leg Syndrome (RLS)
Supplement iron if ferritin <75
Chronic: Dopamine agonists / Gabapentin
Intermittent: Carbidopa-levodopa, low-potency
Treatment of Restless ... Supplement iron if ferritin ... Syndrome #RLS #Treatment ... #management #neurology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• ↓Hgb • High ferritin ... the higher the ferritin ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
cell activity • Ferritin ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
dysfunction, ↑ Ferritin ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... concentration; SF, serum ferritin ... algorithm #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
dehydrogenase • ↑ Ferritin ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Saturation, ↓ Ferritin ... Saturation, ↑-nl Ferritin ... Saturation, ↓-↑-nl Ferritin ... Saturation, ↑-nl Ferritin