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Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
- RDW, FEP, serum iron,

Disease - Laboratory Testing ... - Ferritin-best ... Disease #Laboratory #Testing

Antenatal Visits - Testing and Schedule
At Every Visit:
• Gestational Age
• BP
• Maternal Weight

Antenatal Visits - Testing ... • +/- TSH, Ferritin ... Glucose Tolerance Testing ... Well-being GBS Testing ... Antenatal #Visits #Testing

Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓

Saturation, ↓ Ferritin ... Saturation, ↑-nl Ferritin ... Saturation, ↓-↑-nl Ferritin ... Saturation, ↑-nl Ferritin

Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin

Differential Diagnosis Ferritin ... > 1000 Ferritin ... hepcidin prevents ferritin ... Common Causes Ferritin ... Common Causes Ferritin

Testing for Diabetes Type II
-
Hemoglobin A1c test
- Random blood sugar test
- Fasting

Testing for Diabetes ... sugar test - Fasting ... Classification #Testing

Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,

findings in HLH: ↑↑ ferritin ... consistent with HLH OR Meeting ... cell lines) • ↑ ferritin

Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery
Nutrient Deficiencies:
• Most frequent in the malabsorptive surgeries

inappropriate eating ... Zn, Selenium • Ferritin ... Bone densitometry testing

Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations:
1. HLH
2. Still's disease
3. Systemic

histoplasmosis #Ferritin

Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
• Ferritin <

deficiency if: • Ferritin ... Non-invasive testing

Algorithm for the diagnosis of chronic diarrhea.
It is usually impractical to test and treat the many

diarrhea before testing ... and treating to ... reduce unnecessary testing ... Diarrhea #Algorithm #Testing

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